Understanding how JMJD4 affects breast cancer
Official title: Role of JMJD4 in Breast Cancer
Funded at University of Oklahoma Hlth Sciences Ctr · NIH-11042876 · Data updated 2026-11-12
This study is looking at how a protein called JMJD4 affects breast cancer growth and treatment resistance, with the hope of finding new ways to help patients with breast cancer.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $72,500 |
| NIH project number | 5R03CA289562-02 |
| Project ID | NIH-11042876 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with breast cancer who may benefit from novel treatment approaches.
✕Less likely to help
Patients with non-breast cancer conditions or those who are not currently undergoing treatment for breast cancer may not receive any benefit from this research.
What this research studies
This research investigates the role of an enzyme called JMJD4 in breast cancer, focusing on how it influences tumor growth and resistance to treatment. By studying breast cancer cells, the researchers aim to uncover the mechanisms through which JMJD4 interacts with key proteins involved in cancer progression. The project includes specific experiments to determine JMJD4's function and its relationship with other factors that contribute to breast cancer. This work could lead to new insights and potential therapies for patients with breast cancer.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve treatment outcomes for breast cancer patients.
How similar studies have gone: Previous research has shown promising results in understanding the roles of similar enzymes in cancer biology, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Oklahoma Hlth Sciences Ctr
Oklahoma City, United States Active
Researchers
- Principal investigator: Janknecht, Ralf — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Janknecht, Ralf
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.