Understanding how invasive lobular carcinoma interacts with its surrounding tissue
Official title: Extracellular Matrix Remodeling and the Control of Invasive Lobular Carcinoma Progression
Funded at University of Michigan at Ann Arbor · NIH-11055471 · Data updated 2026-11-12
This study is looking at how a specific type of breast cancer called invasive lobular carcinoma spreads and resists treatment, with the hope of finding better ways to help patients like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | April 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $35,031 |
| NIH project number | 5F31CA275102-03 |
| Project ID | NIH-11055471 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with invasive lobular carcinoma or those at high risk for developing this subtype of breast cancer.
✕Less likely to help
Patients with other types of breast cancer or those without a diagnosis of invasive lobular carcinoma may not benefit from this research.
What this research studies
This research investigates invasive lobular carcinoma (ILC), a common subtype of breast cancer known for its unique growth patterns and resistance to treatment. The study focuses on how ILC cells invade surrounding tissues, particularly the extracellular matrix (ECM), and the role of specific proteins in this process. By examining the interactions between cancer cells and the ECM, researchers aim to uncover mechanisms that contribute to the cancer's invasive behavior and resistance to therapies. Patients may benefit from insights that could lead to improved treatment strategies for ILC.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches that enhance treatment effectiveness for patients with invasive lobular carcinoma.
How similar studies have gone: Previous research has shown promising results in understanding the role of the extracellular matrix in cancer progression, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Olson, Adam Wallace — University of Michigan at Ann Arbor
- Study coordinator: Olson, Adam Wallace
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.