Understanding how intestinal parasites affect herpesvirus infections
Defining Mechanisms for Parasite-Driven Effects on Gamma-Herpesvirus Latency
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11003779
This study is looking at how intestinal parasites might affect the way dormant herpesviruses reactivate in the body, and it’s for anyone interested in understanding how these infections can interact and impact health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11003779 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between intestinal parasites and gamma-herpesvirus infections, focusing on how these parasites can influence the reactivation of herpesviruses from a dormant state. The study aims to determine whether the timing of infections affects the reactivation process, specifically looking at cases where parasites infect before or after herpesvirus infection. By analyzing immune responses and cellular mechanisms involved, the research seeks to uncover important insights into chronic infections that affect a significant portion of the global population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are co-infected with gamma-herpesviruses and intestinal parasites.
Not a fit: Patients who are not infected with either gamma-herpesviruses or intestinal parasites may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing herpesvirus infections in patients co-infected with intestinal parasites.
How similar studies have performed: Previous research has shown that co-infections can significantly alter the behavior of chronic infections, suggesting that this approach may yield valuable insights.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REESE, TIFFANY ANNE — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: REESE, TIFFANY ANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.