Understanding How Interventions Affect Healthy Aging and Longevity

Caenorhabditis Intervention Testing Program: Interventions That Modulate Health, Longevity and Aging Hallmarks

['FUNDING_U01'] · RUTGERS, THE STATE UNIV OF N.J. · NIH-11136907

This research explores different treatments in tiny worms to discover ways that might help people live longer, healthier lives.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorRUTGERS, THE STATE UNIV OF N.J. (nih funded)
Locations1 site (PISCATAWAY, UNITED STATES)
Trial IDNIH-11136907 on ClinicalTrials.gov

What this research studies

Aging brings many health challenges, impacting quality of life for older adults and their families, and increasing the risk for diseases like cancer and diabetes. This project uses a simple animal model, the nematode worm *Caenorhabditis elegans*, to test various compounds that could extend healthy aging and promote longevity. Researchers are specifically looking for treatments that work across a diverse group of these worms, which helps them understand how these treatments might affect the wide genetic differences seen in humans. The ultimate goal is to translate these findings into new approaches for human health.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients, but its findings are intended to benefit individuals concerned with healthy aging and age-related conditions in the future.

Not a fit: Patients seeking immediate treatment for existing conditions will not directly benefit from this early-stage animal model research.

Why it matters

Potential benefit: If successful, this work could identify new treatments or strategies to slow down the aging process and prevent age-related diseases in humans.

How similar studies have performed: Significant progress has been made in the biology of aging using simple animal models, suggesting that many interventions found in worms may have similar effects in humans.

Where this research is happening

PISCATAWAY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.