Understanding how internal states affect decision-making in the brain
Mechanistic neural circuit models and principles
This study looks at how an animal's feelings and focus affect the choices it makes, using a special task to help understand the brain's role in these decisions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906303 on NIH RePORTER |
What this research studies
This research investigates how an animal's internal state, such as its level of engagement, influences its decision-making processes. By utilizing a standardized decision-making task developed by the International Brain Laboratory, the research team aims to create mechanistic models that explain the neural circuits involved in these decisions. The approach includes training animals, measuring neural activity, and analyzing data to understand the relationship between internal states and behavior. This comprehensive methodology seeks to uncover the underlying neural mechanisms that drive decision-making.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions affecting cognitive function or decision-making processes.
Not a fit: Patients with stable cognitive function and no decision-making impairments may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how brain function affects behavior, potentially informing treatments for conditions that impact decision-making.
How similar studies have performed: Previous research in neural circuit modeling has shown promise in understanding decision-making processes, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Columbia Univ New York Morningside — New York, United States (Active)
Researchers
- Principal investigator: Fiete, Ila R. — Columbia Univ New York Morningside
- Study coordinator: Fiete, Ila R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.