Understanding how internal brain states affect decision-making in rodents
P3: Internal Brain States
['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-10900685
This study looks at how different brain conditions affect how mice make choices, helping scientists understand the brain's role in decision-making.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-10900685 on ClinicalTrials.gov |
What this research studies
This research investigates how different internal brain states influence decision-making strategies in rodents. By observing the behavior of mice during sensory decision-making tasks, researchers have developed a statistical model to identify these internal states. The study aims to explore the neural mechanisms behind these states using advanced techniques like large-scale neural recordings and optogenetic inactivation. This approach will help uncover how various brain regions contribute to decision-making under different conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cognitive impairments or disorders that affect decision-making.
Not a fit: Patients without cognitive impairments or those not experiencing decision-making difficulties may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of decision-making processes, potentially informing treatments for cognitive disorders.
How similar studies have performed: Other research has shown promising results in understanding decision-making processes through similar approaches, indicating a potential for significant advancements.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PILLOW, JONATHAN WILLIAM — PRINCETON UNIVERSITY
- Study coordinator: PILLOW, JONATHAN WILLIAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.