Understanding how insulin is cleared from the body
Official title: Novel Molecular Determinants of Insulin Clearance
Funded at Western University of Health Sciences · NIH-11018537 · Data updated 2026-11-12
This study is looking at how the body gets rid of insulin from the blood, especially for people with Type 2 diabetes, to find new ways to help manage insulin levels and improve overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Western University of Health Sciences NIH-funded |
| Lab location | 1 site (Pomona, United States) |
| Project start | April 25, 2022 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $477,742 |
| NIH project number | 5R01DK129877-04 |
| Project ID | NIH-11018537 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Type 2 diabetes who may be experiencing issues with insulin regulation.
✕Less likely to help
Patients without Type 2 diabetes or those with other forms of diabetes may not benefit from this research.
What this research studies
This research investigates the molecular factors that influence how insulin is cleared from the bloodstream, particularly in the context of Type 2 diabetes (T2D). It aims to explore the cellular mechanisms behind insulin clearance and how they relate to insulin resistance and secretion. By studying these processes, the research seeks to uncover potential new therapeutic targets that could improve insulin regulation and overall metabolic health for patients with T2D.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance insulin clearance, potentially improving blood sugar control and reducing complications associated with Type 2 diabetes.
How similar studies have gone: While insulin clearance has been less studied compared to insulin secretion and resistance, there is emerging evidence suggesting that understanding this area could lead to significant advancements in diabetes treatment.
Where this research is happening
-
Western University of Health Sciences
Pomona, United States Active
Researchers
- Principal investigator: Peterfy, Miklos — Western University of Health Sciences
- Study coordinator: Peterfy, Miklos
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.