Understanding how insulin is cleared from the body

Novel Molecular Determinants of Insulin Clearance

['FUNDING_R01'] · WESTERN UNIVERSITY OF HEALTH SCIENCES · NIH-11018537

This study is looking at how the body gets rid of insulin from the blood, especially for people with Type 2 diabetes, to find new ways to help manage insulin levels and improve overall health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWESTERN UNIVERSITY OF HEALTH SCIENCES (nih funded)
Locations1 site (POMONA, UNITED STATES)
Trial IDNIH-11018537 on ClinicalTrials.gov

What this research studies

This research investigates the molecular factors that influence how insulin is cleared from the bloodstream, particularly in the context of Type 2 diabetes (T2D). It aims to explore the cellular mechanisms behind insulin clearance and how they relate to insulin resistance and secretion. By studying these processes, the research seeks to uncover potential new therapeutic targets that could improve insulin regulation and overall metabolic health for patients with T2D.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Type 2 diabetes who may be experiencing issues with insulin regulation.

Not a fit: Patients without Type 2 diabetes or those with other forms of diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that enhance insulin clearance, potentially improving blood sugar control and reducing complications associated with Type 2 diabetes.

How similar studies have performed: While insulin clearance has been less studied compared to insulin secretion and resistance, there is emerging evidence suggesting that understanding this area could lead to significant advancements in diabetes treatment.

Where this research is happening

POMONA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.