Understanding how insomnia affects metabolism based on sleep duration

Metabolic Reprogramming in Insomnia as a Function of Objective Sleep Duration

NIH-funded research University of Pennsylvania · NIH-10864947

This study is looking at how different amounts of sleep affect the metabolism of people with insomnia, hoping to find helpful clues for better diagnosing and treating insomnia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10864947 on NIH RePORTER

What this research studies

This research investigates the relationship between insomnia and metabolic changes, focusing on how different sleep durations impact these metabolic profiles. By analyzing biological markers in individuals with insomnia, the study aims to identify distinct metabolic signatures that could help in diagnosing and treating insomnia more effectively. The research involves detailed assessments of sleep and metabolism in 100 participants, categorized into four groups based on their sleep duration and insomnia status. This approach seeks to enhance our understanding of insomnia and its effects on overall health.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing insomnia, particularly those with varying sleep durations.

Not a fit: Patients who do not have insomnia or those with other sleep disorders unrelated to insomnia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for insomnia, ultimately enhancing patients' quality of life.

How similar studies have performed: Previous research has shown promising results in identifying metabolic changes associated with sleep disturbances, suggesting that this approach may yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.