Understanding how insects detect smells to improve repellents and traps

Molecular Basis of Insect Olfaction

NIH-funded research University of Connecticut Storrs · NIH-11090794

This study is looking at how mosquitoes and other insects smell things around them, using fruit flies to help understand the science behind it, with the hope of creating better repellents and traps to help keep you safe from insect-borne diseases.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project IDNIH-11090794 on NIH RePORTER

What this research studies

This research investigates the molecular and cellular mechanisms that enable insects, particularly mosquitoes, to detect odors in their environment. By studying the olfactory system at the genetic and cellular levels using the fruit fly Drosophila as a model, the research aims to uncover how olfactory neurons respond to various smells. The approach includes genetic manipulation and behavioral assays to identify key signaling molecules involved in insect olfaction. The ultimate goal is to develop more effective repellents and traps to reduce the spread of diseases transmitted by these insects.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals living in areas heavily affected by mosquito-borne diseases.

Not a fit: Patients who do not live in regions impacted by mosquito-borne diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective insect repellents and traps, significantly reducing the incidence of insect-borne diseases.

How similar studies have performed: Previous research has shown success in understanding insect olfaction and developing interventions, indicating that this approach has potential for impactful outcomes.

Where this research is happening

Storrs-Mansfield, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.