Understanding how inhibitory neurons work in the primate visual cortex
Connectivity and function of inhibitory neurons in the primate visual cortex
This study is looking at how certain brain cells that help control visual information work in primates, which could help us understand their role in conditions like autism and anxiety.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10874458 on NIH RePORTER |
What this research studies
This research investigates the connectivity and function of specific types of inhibitory neurons in the visual cortex of primates. By using advanced viral tools to express genes in these neurons, the study aims to uncover how these neurons influence visual processing and their potential roles in various neurological disorders. The research focuses on two major classes of inhibitory neurons, parvalbumin and somatostatin, to understand their unique properties and functions. This work is crucial for translating findings from animal models to human conditions, particularly in understanding disorders like autism and anxiety.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological disorders such as autism, epilepsy, or anxiety.
Not a fit: Patients without neurological disorders or those who do not have a diagnosis related to inhibitory neuron dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for neurological disorders associated with inhibitory neuron dysfunction.
How similar studies have performed: While research on inhibitory neurons has been successful in animal models, this specific approach in primates is relatively novel and untested.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Angelucci, Alessandra — University of Utah
- Study coordinator: Angelucci, Alessandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.