Understanding how influenza viruses evolve and spread in humans
Evolution and Transmission of Influenza Virus in Natural Human Infection
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10873944
This study is looking at how the flu virus changes and spreads among people who are infected and those around them, so we can better understand it and improve future vaccines.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10873944 on ClinicalTrials.gov |
What this research studies
This research investigates the evolution and transmission of influenza viruses in people who are naturally infected. By collecting samples from infected individuals and their close contacts, the study aims to analyze how the virus changes over time and how it spreads within communities. Using advanced molecular techniques, researchers will track the genetic variations of the virus and identify factors that influence its infectivity and transmission. This comprehensive approach will help fill critical knowledge gaps regarding influenza dynamics and inform future vaccine development.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have recently been infected with influenza and their close contacts.
Not a fit: Patients who have not been infected with influenza or those who are not in close contact with infected individuals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective vaccines and strategies to combat influenza epidemics.
How similar studies have performed: Previous research has successfully used similar molecular approaches to study viral evolution and transmission, indicating the potential for meaningful insights in this area.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAURING, ADAM — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: LAURING, ADAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases, Community-Acquired Infections