Understanding how influenza viruses evolve and affect the immune system
NIAID Centers of Excellence for Influenza Research and Response
This study is looking at how different factors affect the spread and changes of flu viruses, including those from birds, and it aims to understand how our immune system reacts to flu infections and vaccines, so we can better protect ourselves and respond to the flu.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11303227 on NIH RePORTER |
What this research studies
This research investigates the factors that influence the evolution and transmission of influenza viruses, including avian strains. It aims to characterize the immune response to influenza infections and vaccinations through cohort studies and sampling from both humans and animals. By identifying the immunological factors that determine disease outcomes, the research seeks to enhance our understanding of how to protect against and respond to influenza infections effectively.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals who have been exposed to influenza or are at risk of infection, as well as those involved in vaccination programs.
Not a fit: Patients who are not at risk for influenza or have no history of exposure to the virus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for influenza, enhancing protection against various strains of the virus.
How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has the potential for meaningful advancements.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Garcia-Sastre, Adolfo — Icahn School of Medicine at Mount Sinai
- Study coordinator: Garcia-Sastre, Adolfo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.