Understanding how influenza viruses evolve and affect the immune response
NIAID Centers of Excellence for Influenza Research and Response
This study looks at how the flu virus spreads and how our bodies fight it, using information from both people and animals, to help make vaccines better and improve how we respond to flu outbreaks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11259407 on NIH RePORTER |
What this research studies
This research investigates the factors that influence the evolution and transmission of influenza viruses, as well as the immune response to these infections. It involves cohort studies and sampling from both humans and animals to gather data on how influenza spreads and how effective vaccinations are. By identifying the immunological factors that affect disease outcomes, the research aims to enhance our understanding of protection against influenza. This could lead to improved vaccination strategies and better public health responses to flu outbreaks.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals who are at risk of influenza infection, such as those with compromised immune systems or chronic health conditions.
Not a fit: Patients who are not at risk for influenza or who have already been vaccinated may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines and better strategies for preventing flu outbreaks.
How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for significant advancements.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Hensley, Scott — University of Pennsylvania
- Study coordinator: Hensley, Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.