Understanding how influenza viruses evolve and affect the immune response

NIAID Centers of Excellence for Influenza Research and Response

['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11070180

This study is looking at how flu viruses change, spread, and make people sick, by studying both humans and animals, to help us understand how to better protect ourselves and improve flu vaccines.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11070180 on ClinicalTrials.gov

What this research studies

This research investigates the factors that influence the evolution, transmission, and pathogenicity of influenza viruses. It involves cohort studies and sampling from both humans and animals to gain insights into how these viruses spread and how the immune system responds to them. By identifying the immunological factors that determine the outcomes of influenza infections and vaccinations, the research aims to enhance our understanding of protection against the virus and improve vaccination strategies.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who are at risk of influenza infection, such as those with compromised immune systems or chronic health conditions.

Not a fit: Patients who are not at risk for influenza or those who have already been vaccinated may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective influenza vaccines and better strategies for preventing and treating influenza infections.

How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for significant advancements.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.