Understanding how influenza viruses evolve and affect the immune response

NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE

NIH-funded research St. Jude Children's Research Hospital · NIH-10788192

This study is looking at how the flu virus changes and spreads, and how our immune system responds to it, so we can better understand how to protect people and animals from getting sick and improve flu vaccines.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Jude Children's Research Hospital NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-10788192 on NIH RePORTER

What this research studies

This research investigates the factors that influence the evolution, transmission, and pathogenicity of influenza viruses, particularly focusing on the immune response to infections. It involves cohort studies and sampling from both humans and animals to gather data on how influenza spreads and how effective vaccinations are. The goal is to identify the immunological factors that contribute to protection against influenza and to enhance our understanding of cross-protection between different strains.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who are at risk of influenza infection, such as those with compromised immune systems or chronic health conditions.

Not a fit: Patients who are not at risk for influenza or who have already been vaccinated may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved influenza vaccines and better strategies for preventing and treating influenza infections.

How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for significant advancements.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease OutcomeNational Institute of Allergy and Infectious Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.