Understanding how influenza viruses evolve and affect humans and animals

NIAID Centers of Excellence for Influenza Research and Response

NIH-funded research University of Pennsylvania · NIH-11065379

This study is looking at how the flu virus changes and spreads among people and animals, and it wants to understand how our immune systems respond to the flu and vaccines so we can create better ways to protect everyone from getting sick.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11065379 on NIH RePORTER

What this research studies

This research investigates the factors that influence the evolution and transmission of influenza viruses, focusing on both human and animal populations. It aims to characterize the immune response to influenza infections and vaccinations, which could lead to better protection strategies. The research involves cohort studies and sampling from both humans and animals to gather data on how influenza viruses adapt and spread. By identifying key immunological factors, the study seeks to improve vaccination effectiveness and disease outcomes.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who are at risk of influenza infection, such as those with compromised immune systems or chronic health conditions.

Not a fit: Patients who are not at risk for influenza or those who have already been vaccinated may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccines and strategies for preventing influenza infections in both humans and animals.

How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for significant advancements.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.