Understanding how influenza A virus spreads in humans
Official title: Modeling Core - Drivers of influenza A virus transmission in humans
Funded at Emory University · NIH-11010623 · Data updated 2026-11-12
This study is looking at how the flu virus interacts with our immune system to figure out how it spreads from person to person, which could help us find better ways to prevent and treat the flu.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | April 18, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $414,941 |
| NIH project number | 1P01AI186819-01 |
| Project ID | NIH-11010623 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals who are at high risk for influenza infection, such as those with compromised immune systems or chronic health conditions.
✕Less likely to help
Patients who are not affected by influenza or who have no risk factors for severe influenza illness may not receive any benefit from this research.
What this research studies
This research investigates the complex interactions between the immune response and the influenza A virus to better understand how the virus transmits between individuals. By using advanced modeling techniques, the team will analyze data on viral dynamics and immune responses to identify key factors that influence the spread of the virus. The goal is to develop models that can predict how the virus behaves within hosts and how it is expelled into the environment, which is crucial for controlling outbreaks. Patients may benefit from insights gained that could lead to improved prevention and treatment strategies for influenza.
Why it matters
Potential benefit: If successful, this research could lead to better strategies for preventing and controlling influenza outbreaks, ultimately improving patient health outcomes.
How similar studies have gone: Previous research has shown success in using modeling approaches to understand viral transmission dynamics, indicating that this method is both valid and promising.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Koelle, Katharina V — Emory University
- Study coordinator: Koelle, Katharina V
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.