Understanding how influenza A virus spreads in humans
Drivers of influenza A virus transmission in humans
This study is looking at how the flu virus spreads in people by observing how it behaves in the body and how it can be passed from person to person, so we can better understand the infection and help keep everyone healthier.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11010621 on NIH RePORTER |
What this research studies
This research investigates the transmission of influenza A virus (IAV) in humans by using a controlled human infection model. The study aims to analyze how the virus behaves in the body, including how much virus is produced, the immune response, and how aerosols contribute to spreading the virus. By closely monitoring infected individuals over time, researchers will gather detailed data on the infection process and its variability among different people. This comprehensive approach will help identify key factors that influence the transmission of the virus.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy adults who are willing to participate in a controlled infection study.
Not a fit: Patients with underlying health conditions or those who are immunocompromised may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective strategies for preventing the spread of influenza A virus, ultimately reducing illness and improving public health.
How similar studies have performed: Previous research using controlled human infection models has shown promise in understanding viral transmission, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Lowen, Anice C — Emory University
- Study coordinator: Lowen, Anice C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.