NIH-funded research P01 program project

Understanding how influenza A virus spreads in humans

Official title: Drivers of influenza A virus transmission in humans

Funded at Emory University · NIH-11010621 · Data updated 2026-11-12

This study is looking at how the flu virus spreads in people by observing how it behaves in the body and how it can be passed from person to person, so we can better understand the infection and help keep everyone healthier.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startApril 18, 2025
Project endMarch 31, 2030
Funding year2025
Award (this year)$2,074,701
NIH project number1P01AI186819-01
Project IDNIH-11010621 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are healthy adults who are willing to participate in a controlled infection study.

Less likely to help

Patients with underlying health conditions or those who are immunocompromised may not benefit from this research.

What this research studies

This research investigates the transmission of influenza A virus (IAV) in humans by using a controlled human infection model. The study aims to analyze how the virus behaves in the body, including how much virus is produced, the immune response, and how aerosols contribute to spreading the virus. By closely monitoring infected individuals over time, researchers will gather detailed data on the infection process and its variability among different people. This comprehensive approach will help identify key factors that influence the transmission of the virus.

Why it matters

Potential benefit: If successful, this research could lead to more effective strategies for preventing the spread of influenza A virus, ultimately reducing illness and improving public health.

How similar studies have gone: Previous research using controlled human infection models has shown promise in understanding viral transmission, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Lowen, Anice C — Emory University
  • Study coordinator: Lowen, Anice C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.