Understanding how influenza A virus spreads among humans
Official title: Clinical Core: Drivers of influenza A virus transmission in humans
Funded at Emory University · NIH-11010624 · Data updated 2026-11-12
This study is looking for volunteers to help us understand how the flu virus spreads by exposing them to it in a safe way, so we can learn more about preventing future outbreaks and keeping everyone healthier.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | April 18, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $414,941 |
| NIH project number | 1P01AI186819-01 |
| Project ID | NIH-11010624 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are healthy adults who are willing to be exposed to the influenza virus in a controlled setting.
✕Less likely to help
Patients with compromised immune systems or those with a history of severe allergic reactions to influenza vaccines may not benefit from this research.
What this research studies
This research investigates the factors that influence the transmission of the influenza A virus using a controlled human infection model. Participants will be exposed to the virus through various methods, including intranasal inoculation and aerosolization, to gather data on how the virus spreads. The study aims to collect samples and clinical data to better understand the virological, immunological, and behavioral aspects of transmission. By participating, individuals will contribute to vital research that could inform public health strategies for preventing future outbreaks.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and controlling influenza outbreaks, ultimately enhancing public health.
How similar studies have gone: Previous research using controlled human infection models has shown promise in understanding viral transmission dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Rouphael, Nadine Georges — Emory University
- Study coordinator: Rouphael, Nadine Georges
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.