Understanding how inflammation causes anemia in burn patients
Official title: Inflammatory Mechanisms in Post Burn Anemia of Critical Illness
Funded at University of Cincinnati · NIH-11010769 · Data updated 2026-11-12
This study is looking at why people with severe burns often have anemia, especially how inflammation might be making it harder for their bodies to produce red blood cells, and it aims to find new ways to help reduce the need for blood transfusions during their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | January 1, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $368,436 |
| NIH project number | 5R01HL155579-04 |
| Project ID | NIH-11010769 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have experienced severe burns and are suffering from anemia as a result.
✕Less likely to help
Patients who do not have anemia or have not experienced severe burns may not benefit from this research.
What this research studies
This research investigates the causes of anemia in patients who have suffered severe burns, particularly focusing on how inflammation affects their blood production. The study aims to identify specific inflammatory mechanisms that lead to reduced red blood cell production and increased need for blood transfusions. By exploring the roles of certain signaling molecules in the body, the researchers hope to develop new treatments that could lessen the need for blood transfusions in these patients. This could ultimately improve recovery outcomes for burn victims in critical care settings.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that reduce the need for blood transfusions in burn patients, improving their recovery and overall health outcomes.
How similar studies have gone: Previous research has shown that understanding inflammatory mechanisms can lead to successful interventions in similar conditions, suggesting potential for success in this area as well.
Where this research is happening
-
University of Cincinnati
Cincinnati, United States Active
Researchers
- Principal investigator: Gardner, Jason — University of Cincinnati
- Study coordinator: Gardner, Jason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.