Understanding how inflammation and metabolic health relate to colorectal cancer risk
Metabolomic signatures of inflammation and metabolic health in relation to colorectal cancer risk
This study is looking at how inflammation and metabolic health might affect the risk of developing colorectal cancer, using data from large health studies to find specific signs that could help us understand the links between diet, inflammation, and cancer risk.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10907712 on NIH RePORTER |
What this research studies
This research investigates the connections between inflammation, metabolic health, and the risk of developing colorectal cancer (CRC). By analyzing data from large cohorts, including the Nurses’ Health Study and the Health Professionals Follow-up Study, the researchers aim to identify specific metabolomic signatures that indicate inflammation and metabolic health. They will employ advanced statistical methods to uncover patterns in biological markers and lifestyle factors that may influence CRC risk. The ultimate goal is to better understand the biological mechanisms linking diet, inflammation, and metabolic health to CRC.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of colorectal cancer or those exhibiting signs of metabolic disturbance or chronic inflammation.
Not a fit: Patients who are not at risk for colorectal cancer or do not have metabolic health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing colorectal cancer by identifying at-risk individuals based on their metabolic and inflammatory profiles.
How similar studies have performed: Previous research has shown promising results in understanding the links between inflammation, metabolic health, and cancer risk, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Bever, Alaina — Harvard Medical School
- Study coordinator: Bever, Alaina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.