Understanding how inflammation affects pancreatic diseases
Official title: Unraveling the Role of NADPH Oxidase in Inflammation-associated Pancreatic Diseases
Funded at University of Texas El Paso · NIH-10630189 · Data updated 2026-11-12
This study is looking at how inflammation affects pancreatic diseases, like pancreatitis and pancreatic cancer, to find new ways to prevent and treat these conditions, which could help patients in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas El Paso NIH-funded |
| Lab location | 1 site (El Paso, United States) |
| Project start | September 1, 2020 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $331,560 |
| NIH project number | 5R01DK123079-05 |
| Project ID | NIH-10630189 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with pancreatic inflammation, pancreatitis, or related pancreatic disorders.
✕Less likely to help
Patients with non-inflammatory pancreatic conditions or those without any pancreatic disease may not benefit from this research.
What this research studies
This research investigates the role of inflammation in pancreatic diseases, focusing on how reactive oxygen species (ROS) contribute to conditions like pancreatitis and pancreatic cancer. By examining the molecular mechanisms involved, particularly the behavior of mutant KRAS genes under inflammatory conditions, the study aims to uncover new therapeutic targets. Patients may benefit from insights that could lead to better prevention and treatment strategies for pancreatic disorders. The research employs a combination of laboratory experiments and analysis of genetic factors related to inflammation.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from pancreatic diseases linked to inflammation.
How similar studies have gone: Previous research has shown promising results in understanding the role of inflammation in pancreatic diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Texas El Paso
El Paso, United States Active
Researchers
- Principal investigator: Lu, Weiqin — University of Texas El Paso
- Study coordinator: Lu, Weiqin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.