Understanding how inflammation affects healing in the mouth
Deciphering Inflammatory Regulation of Oral Epithelial Progenitor Cells During Oral Mucosal Regeneration
This study is looking at how the inside of your mouth heals faster than your skin and what happens when inflammation gets in the way, which could help improve treatments for conditions like mouth sores and gum disease.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10834756 on NIH RePORTER |
What this research studies
This research investigates the unique healing properties of the oral mucosa, which heals faster than skin and has a suppressed inflammatory response. It aims to uncover the cellular mechanisms that enable rapid regeneration and how chronic inflammation can disrupt this process, leading to conditions like oral mucositis and periodontitis. By studying oral epithelial progenitor cells, the research seeks to understand how these cells contribute to wound healing and what happens when inflammation interferes with their function. This could provide insights into improving treatments for chronic oral wounds.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic oral wounds or conditions that affect oral healing, such as periodontitis or oral mucositis.
Not a fit: Patients without chronic oral conditions or those who do not experience issues with oral healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments for chronic oral wounds, improving nutrition and quality of life for affected patients.
How similar studies have performed: Previous research has shown promising results in understanding wound healing in other tissues, but this specific focus on oral mucosa is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Cook, Jessica — University of California, San Francisco
- Study coordinator: Cook, Jessica
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.