Understanding how inflammation affects cognitive deficits in fetal alcohol spectrum disorders.
Neuroinflammation: Role in FASD Cognitive Deficits
This study is looking at how inflammation in the brain affects thinking and learning problems in kids with fetal alcohol spectrum disorders (FASD), and it hopes to find ways to help improve these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Arkansas for Med Scis NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10476622 on NIH RePORTER |
What this research studies
This research investigates the impact of neuroinflammation on cognitive deficits associated with fetal alcohol spectrum disorders (FASD). By studying animal models, the researchers aim to uncover the molecular mechanisms that lead to neurological issues caused by alcohol exposure during development. They will explore how inflammation in the brain, particularly in the hippocampus, contributes to long-term cognitive impairments. Additionally, the study will evaluate potential pharmaceutical interventions that could mitigate these effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have been diagnosed with fetal alcohol spectrum disorders and experience cognitive deficits.
Not a fit: Patients who do not have fetal alcohol spectrum disorders or related cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function in individuals affected by fetal alcohol spectrum disorders.
How similar studies have performed: Previous research has shown that targeting neuroinflammation can lead to improvements in cognitive function in various neurological conditions, suggesting a promising avenue for this study.
Where this research is happening
Little Rock, United States
- Univ of Arkansas for Med Scis — Little Rock, United States (Active)
Researchers
- Principal investigator: Drew, Paul D — Univ of Arkansas for Med Scis
- Study coordinator: Drew, Paul D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.