Understanding how infants and young children respond to respiratory viruses like SARS-CoV-2 and influenza.
Project 2
This study is looking at how babies and young kids respond to respiratory viruses like COVID-19 and the flu, to help us understand why they might be less sick from these infections and improve their immune health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11065463 on NIH RePORTER |
What this research studies
This research investigates the immune responses of infants and young children to respiratory viruses, particularly focusing on SARS-CoV-2 and influenza. By utilizing advanced systems biology tools, the study aims to analyze the immune system's transcriptome and epigenome, as well as the function of immune cell populations. The research will leverage innovative technologies to capture detailed immune responses in young patients, providing insights into why infants may be less affected by certain infections. The goal is to enhance our understanding of the developing immune system and its reactions to viral infections and vaccinations.
Who could benefit from this research
Good fit: Ideal candidates for participation include infants and young children, particularly those under 11 years old, who are at risk for respiratory infections.
Not a fit: Patients who are older adults or those not within the pediatric age range may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for protecting infants and young children from severe respiratory infections.
How similar studies have performed: Previous research has shown success in understanding immune responses in pediatric populations, making this approach both relevant and promising.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Pascual, Maria Virginia — St. Jude Children's Research Hospital
- Study coordinator: Pascual, Maria Virginia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.