Understanding how infant RSV infection leads to childhood asthma and allergies
Viral and Host Determinants of Infant and Childhood Allergy and Asthma
This research looks at how respiratory syncytial virus (RSV) infections in babies might cause asthma and allergies later in childhood, aiming to find ways to prevent these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11115691 on NIH RePORTER |
What this research studies
We know that babies who get severe RSV infections are more likely to develop asthma as they grow up, but we don't fully understand why. This project explores how RSV infection changes a baby's body, specifically looking at how it affects the developing airway and immune system. We are focusing on changes in DNA and how cells in the airway function, using information from large groups of children followed since birth. By understanding these connections, we hope to discover new ways to protect children from asthma and allergies.
Who could benefit from this research
Good fit: This research is relevant for infants and young children who have experienced RSV infection and are at risk for developing asthma or allergies.
Not a fit: Patients who are adults or those without a history of infant RSV infection or risk for childhood asthma may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new strategies for preventing asthma and allergies in children who have had RSV infections as infants.
How similar studies have performed: Prior studies have shown a strong link between infant RSV infection and later asthma risk, and this research builds upon those findings to uncover the specific biological mechanisms involved.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Hartert, Tina V — Vanderbilt University Medical Center
- Study coordinator: Hartert, Tina V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.