Understanding how infant brains develop and work

Brain structure and function in infants

NIH-funded research Children's Hosp of Philadelphia · NIH-11195640

This project helps us learn about how babies' brains grow and change, and how that affects their behavior.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11195640 on NIH RePORTER

What this research studies

For many years, scientists have looked at brain activity in adults, especially during rest, to understand how the brain gets ready to process information. It's harder to do this with babies because they often move or open their eyes, which makes it difficult to get clear measurements. Our team has created new ways to overcome these challenges, allowing us to better observe how brain function, structure, and chemistry mature in infants. This helps us connect these brain changes to a baby's behavior and overall development.

Who could benefit from this research

Good fit: This research focuses on infants and toddlers, specifically those in the 0-11 years old age range.

Not a fit: Patients seeking immediate treatment for a specific condition may not directly benefit from this foundational research.

Why it matters

Potential benefit: If successful, this work could lead to a better understanding of typical brain development and help identify early signs of developmental differences or clinical disorders in infants.

How similar studies have performed: While previous studies have explored resting-state brain activity, this project builds on new methods developed by the team to overcome long-standing challenges in infant brain research.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.