Understanding how infant brain development is affected by perinatal stroke.
Perinatal Stroke: Longitudinal Assessment of Infant Brain Organization and Recovery through Neuroexcitability, Neuroimaging and Motor Development
This study is looking at how a stroke that happens around the time of birth affects babies' brain development and movement skills during their first two years, and it’s for families with infants who have had a perinatal stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10865141 on NIH RePORTER |
What this research studies
This research investigates the impact of perinatal stroke on infant brain organization and motor development over the first two years of life. By using non-invasive brain stimulation, neuroimaging, and behavioral assessments, the study aims to identify indicators of recovery that could inform future interventions. Researchers will follow 50 infants diagnosed with perinatal stroke from local neonatal intensive care units, assessing their brain excitability and connectivity at four different time points. The goal is to correlate these measures with motor development and potential cerebral palsy diagnoses to understand recovery patterns.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants diagnosed with perinatal stroke who are under two years of age.
Not a fit: Patients who are older than two years or those without a diagnosis of perinatal stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early interventions for infants affected by perinatal stroke, enhancing their recovery and motor development.
How similar studies have performed: Previous research has shown promise in understanding brain recovery in infants, but this specific approach is relatively novel.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Gillick, Bernadette Therese — University of Wisconsin-Madison
- Study coordinator: Gillick, Bernadette Therese
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.