Understanding how immunity to SARS-CoV-2 works in older adults
Mechanisms and Duration of Immunity to SARS-CoV-2
This study is looking at how older adults' immune systems react to COVID-19, whether they've been infected or vaccinated, to understand what helps them build strong, lasting protection against the virus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10854997 on NIH RePORTER |
What this research studies
This research investigates the immune responses of older adults to the SARS-CoV-2 virus, focusing on how their bodies respond to both natural infection and vaccination. The study will analyze blood samples to assess the activity of immune cells, including B cells and T cells, which are crucial for fighting infections. By comparing responses from different patient groups, especially those who are medically underserved, the research aims to uncover what factors contribute to long-lasting immunity. The findings will help inform better treatment and prevention strategies for COVID-19 in older populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those who have experienced COVID-19 or received a COVID-19 vaccine.
Not a fit: Patients who are younger than 65 years old or those who have not been exposed to SARS-CoV-2 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and therapies that enhance immunity against COVID-19 in older adults.
How similar studies have performed: Previous research has shown promising results in understanding immune responses to other viruses, suggesting that this approach could yield valuable insights for SARS-CoV-2 as well.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Boyd, Scott Dexter — Stanford University
- Study coordinator: Boyd, Scott Dexter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.