Understanding how immune responses affect lung health during viral infections
Official title: Type 1-2 immune cross-regulation in the lung
Funded at University of California, San Francisco · NIH-10996003 · Data updated 2026-11-12
This study is looking at how asthma and other allergies affect the way our immune cells work in the lungs when we get sick with viruses like the flu or COVID-19, and it hopes to find new ways to help people breathe better and recover faster.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 13, 2024 |
| Project end | September 12, 2026 |
| Funding year | 2024 |
| Award (this year) | $45,909 |
| NIH project number | 1F31HL172636-01A1 |
| Project ID | NIH-10996003 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with asthma or allergic conditions who are at risk for severe respiratory infections.
✕Less likely to help
Patients without asthma or allergic conditions may not receive direct benefits from this research.
What this research studies
This research investigates the complex interactions between different immune cells in the lungs, particularly focusing on how allergic conditions like asthma influence the severity of respiratory viral infections. By examining the behavior of specific immune cells, the study aims to uncover how these cells respond to infections such as Influenza A and COVID-19. The researchers will utilize advanced 3-D imaging techniques to visualize immune cell distribution and function in lung tissues, providing insights into how these processes affect lung health and recovery. Patients may benefit from a better understanding of their conditions and potential new treatment strategies based on immune responses.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with asthma and allergies, particularly during viral infections.
How similar studies have gone: Previous research has shown promising results in understanding immune responses in respiratory infections, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Caryotakis, Sofia — University of California, San Francisco
- Study coordinator: Caryotakis, Sofia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.