Understanding how immune responses affect lung health during viral infections
Type 1-2 immune cross-regulation in the lung
This study is looking at how asthma and other allergies affect the way our immune cells work in the lungs when we get sick with viruses like the flu or COVID-19, and it hopes to find new ways to help people breathe better and recover faster.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10996003 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between different immune cells in the lungs, particularly focusing on how allergic conditions like asthma influence the severity of respiratory viral infections. By examining the behavior of specific immune cells, the study aims to uncover how these cells respond to infections such as Influenza A and COVID-19. The researchers will utilize advanced 3-D imaging techniques to visualize immune cell distribution and function in lung tissues, providing insights into how these processes affect lung health and recovery. Patients may benefit from a better understanding of their conditions and potential new treatment strategies based on immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with asthma or allergic conditions who are at risk for severe respiratory infections.
Not a fit: Patients without asthma or allergic conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with asthma and allergies, particularly during viral infections.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in respiratory infections, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Caryotakis, Sofia — University of California, San Francisco
- Study coordinator: Caryotakis, Sofia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.