Understanding how immune responses affect cancer treatment outcomes
Core B: Animal Model and Immunotyping Core
['FUNDING_P01'] · CLEVELAND CLINIC LERNER COM-CWRU · NIH-10910034
This study is looking at how immune cells and their signals interact in tumors to better understand how different cancers grow and respond to treatments, which could help doctors create more personalized therapies for patients like you.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEVELAND CLINIC LERNER COM-CWRU (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-10910034 on ClinicalTrials.gov |
What this research studies
This research focuses on the interactions between various immune cells and cytokines in the tumor microenvironment, which can influence how tumors grow and respond to therapies. By standardizing protocols for creating animal models and analyzing immune responses, the project aims to provide a clearer understanding of how different cancers react to treatments. Patients may benefit from insights gained through this research, as it could lead to improved therapeutic strategies tailored to individual immune profiles. The research employs advanced techniques like flow cytometry and single-cell sequencing to accurately assess immune cell types and their roles in cancer progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with various types of cancer who are undergoing treatment and may benefit from enhanced understanding of their immune response.
Not a fit: Patients with non-cancerous conditions or those not currently receiving cancer treatment may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by personalizing therapy based on immune responses.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in cancer, indicating that this approach has potential for significant advancements.
Where this research is happening
CLEVELAND, UNITED STATES
- CLEVELAND CLINIC LERNER COM-CWRU — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAMILTON, THOMAS A. — CLEVELAND CLINIC LERNER COM-CWRU
- Study coordinator: HAMILTON, THOMAS A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.