Understanding how immune responses affect blood platelet levels

Molecular Mechanisms of Immune Thrombocytopenia in Transfusion Medicine

NIH-funded research Versiti Wisconsin, INC. · NIH-10934140

This study is looking into how the immune system affects low platelet counts and blood clotting issues, with the goal of finding better treatments for people of all ages, from newborns to adults.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionVersiti Wisconsin, INC. NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-10934140 on NIH RePORTER

What this research studies

This research investigates the molecular mechanisms behind immune-mediated conditions that lead to low platelet counts and blood clotting disorders. It involves a collaborative effort between experts in platelet immunology and B cell biology, focusing on how these immune responses can impact patients of all ages, including newborns and adults. The research aims to uncover the underlying causes of these conditions to improve treatment options and patient outcomes in transfusion medicine.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with immune-mediated thrombocytopenia or related thrombotic disorders, spanning from newborns to adults.

Not a fit: Patients with non-immune related causes of low platelet counts or those without any blood disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better management and treatment strategies for patients suffering from immune-related blood disorders.

How similar studies have performed: Previous research in platelet immunology and related fields has shown promise in understanding and treating similar conditions, indicating a strong foundation for this investigation.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.