Understanding how immune memory works in cancer treatment
Investigating CD4+ T cell memory in cancer immunotherapy
This study is looking at how the immune system remembers cancer and what can help or hurt that memory, so we can create better treatments for cancer patients.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11144130 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind immune memory in cancer patients, focusing on how it can be initiated and disrupted. Using mouse models and patient samples, the study aims to uncover the biological processes that contribute to effective immunotherapy responses. The research will involve advanced techniques such as transcriptomics and clinical trials to gather comprehensive data. By enhancing our understanding of immune memory, the project seeks to inform the development of more effective cancer treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are undergoing or considering immunotherapy treatments.
Not a fit: Patients with non-cancerous conditions or those not receiving immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved immunotherapy strategies that enhance long-term tumor control in cancer patients.
How similar studies have performed: Previous research has shown promising results in understanding immune memory in cancer, suggesting that this approach could lead to significant advancements.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Wattenberg, Max — Washington University
- Study coordinator: Wattenberg, Max
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.