Understanding how immune cells help heal wounds
Macrophage Phenotypes and Tissue Repair
This study is looking at how certain immune cells help wounds heal, especially in people with diabetes, to find better ways to support healing for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11090856 on NIH RePORTER |
What this research studies
This research investigates the different roles of immune cells, particularly monocytes, macrophages, and Natural Killer cells, in the process of wound healing. By studying both normal and impaired healing in diabetic models, the research aims to uncover how these cells proliferate and communicate during the healing process. Advanced techniques like lineage tracing and spatial transcriptomics will be used to map the behavior of these cells in real-time as wounds heal. The findings could lead to new insights into improving wound healing in patients with diabetes and other conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with diabetic wounds or those experiencing impaired wound healing.
Not a fit: Patients with non-diabetic wounds or those without any wound healing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for wound healing, particularly for patients with diabetes.
How similar studies have performed: Other research has shown promising results in understanding immune cell roles in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Koh, Timothy J — University of Illinois at Chicago
- Study coordinator: Koh, Timothy J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.