Understanding how immune cells function in lung diseases
Official title: Defining the temporospatial functions of neutrophils in acute airspace disease
Funded at Northwestern University at Chicago · NIH-10993516 · Data updated 2026-11-12
This study is looking at how a type of immune cell called neutrophils helps the lungs respond to injuries like pneumonia and infections, with the goal of finding better ways to treat lung diseases that could help patients feel better.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $44,187 |
| NIH project number | 1F31HL172345-01A1 |
| Project ID | NIH-10993516 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from acute lung injuries, such as those caused by aspiration pneumonia or bacterial infections.
✕Less likely to help
Patients with chronic lung diseases or those not experiencing acute inflammatory responses may not benefit from this research.
What this research studies
This research investigates the role of neutrophils, a type of immune cell, in responding to acute lung injuries such as aspiration pneumonia and bacterial infections. It focuses on how these cells migrate from the bloodstream into the lungs and their various functions in both fighting infections and potentially causing further damage. By studying the interactions between neutrophils and the lung tissue, the research aims to uncover critical mechanisms that could lead to better treatments for lung diseases. Patients may benefit from insights gained into how to modulate immune responses for improved outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance the healing process in patients with acute lung injuries.
How similar studies have gone: Previous research has shown promising results in understanding immune cell functions in other inflammatory conditions, suggesting potential for success in this area as well.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Haynes, Maureen — Northwestern University at Chicago
- Study coordinator: Haynes, Maureen
Related research
Other NIH-funded projects on the same topics.
-
High-intensity exercise as a treatment for Parkinson's disease
This study is looking at whether doing high-intensity endurance exercise can help people who have just been diagnosed with Parkinson's disease feel better and slow down their symptoms, especially since current medications don't always do the trick.
-
Software to quickly assess organ dose after radionuclide exposure
This study is creating a helpful software tool that quickly calculates how much radiation your organs absorb after you've taken certain radioactive substances, so you can get better care and treatment based on your individual needs.
-
Investigating innovative approaches to improve health outcomes.
This study is looking for better ways to improve your care and treatment, so you can get more personalized options that work best for you.
-
Investigating innovative approaches to improve health outcomes.
This study is looking for new ways to improve care and treatment for patients, and if you join, you might help test some exciting new methods that could lead to better health for everyone.
-
Investigating innovative approaches to improve health outcomes.
This study is looking for ways to improve care and treatment for patients like you, by trying out new methods that could help manage your health better.
-
Investigating core biological processes
This study is all about exploring important biological processes that affect our health, and it invites patients to help discover new ways to improve care for everyone.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.