Understanding how immune cells function in lung diseases
Defining the temporospatial functions of neutrophils in acute airspace disease
['FUNDING_FELLOWSHIP'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10993516
This study is looking at how a type of immune cell called neutrophils helps the lungs respond to injuries like pneumonia and infections, with the goal of finding better ways to treat lung diseases that could help patients feel better.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY AT CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10993516 on ClinicalTrials.gov |
What this research studies
This research investigates the role of neutrophils, a type of immune cell, in responding to acute lung injuries such as aspiration pneumonia and bacterial infections. It focuses on how these cells migrate from the bloodstream into the lungs and their various functions in both fighting infections and potentially causing further damage. By studying the interactions between neutrophils and the lung tissue, the research aims to uncover critical mechanisms that could lead to better treatments for lung diseases. Patients may benefit from insights gained into how to modulate immune responses for improved outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from acute lung injuries, such as those caused by aspiration pneumonia or bacterial infections.
Not a fit: Patients with chronic lung diseases or those not experiencing acute inflammatory responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance the healing process in patients with acute lung injuries.
How similar studies have performed: Previous research has shown promising results in understanding immune cell functions in other inflammatory conditions, suggesting potential for success in this area as well.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY AT CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAYNES, MAUREEN — NORTHWESTERN UNIVERSITY AT CHICAGO
- Study coordinator: HAYNES, MAUREEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Lung Injury, Acute Pulmonary Injury