Understanding how immune cells can be used to treat cancer and infections
Elucidating Mechanisms of CAR ML NK cell biology to treat cancer and infection
This study is looking at how special immune cells called CAR modified natural killer (NK) cells can be used to better treat cancer and fight infections, so we can find new ways to help patients feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Saint Louis University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11014320 on NIH RePORTER |
What this research studies
This research investigates the biology of CAR modified natural killer (NK) cells and their potential to enhance cancer treatment and fight infections. The approach focuses on understanding how these immune cells function and how they can be effectively utilized in adoptive cell therapy. By studying the mechanisms that regulate NK cell activity, the research aims to improve their effectiveness as a therapeutic option for patients. The project will involve both laboratory experiments and analysis of immune responses in various models.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancer or severe infections who may benefit from advanced immunotherapy treatments.
Not a fit: Patients with conditions that do not involve cancer or infections may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer therapies and improved outcomes for patients with infections.
How similar studies have performed: Previous research has shown promising results in using CAR modified immune cells for cancer treatment, indicating that this approach has potential for success.
Where this research is happening
Saint Louis, United States
- Saint Louis University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Elliott, Melissa Berrien — Saint Louis University
- Study coordinator: Elliott, Melissa Berrien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.