Understanding how immune cells are activated in lupus
Investigating monocyte activation pathways in lupus
This study is looking at how the immune system works in people with lupus, especially how certain immune cells can become overactive and cause problems, and it invites patients to help by sharing samples or information to better understand their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11077246 on NIH RePORTER |
What this research studies
This research investigates the immune system's response in patients with systemic lupus erythematosus (SLE), focusing on how certain immune cells, particularly monocytes, become activated and contribute to the disease. By examining the pathways that lead to the production of inflammatory molecules, the study aims to uncover the mechanisms behind tissue damage in lupus. Patients may be involved in providing samples or data that help researchers understand the role of these immune responses in their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with systemic lupus erythematosus.
Not a fit: Patients with other autoimmune diseases or those without a diagnosis of lupus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better manage or even prevent tissue damage in lupus patients.
How similar studies have performed: Previous research has shown promising results in understanding immune pathways in lupus, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Kang, Insoo — Yale University
- Study coordinator: Kang, Insoo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.