Understanding how immune cells affect nerve recovery after injury
Microglial Activity on Injured Motoneurons
['FUNDING_FELLOWSHIP'] · EMORY UNIVERSITY · NIH-11232651
This study is looking at how special immune cells in the nervous system help nerve cells recover after injuries, which could lead to better treatments for conditions like ALS and help people heal from nerve damage.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11232651 on ClinicalTrials.gov |
What this research studies
This research investigates the role of microglia, a type of immune cell in the nervous system, in the recovery of motoneurons after peripheral nerve injuries. By using advanced imaging techniques, the study aims to visualize how these cells interact with injured motoneurons and how these interactions influence the fate of the neurons, whether they survive or die. The research will also explore the signaling mechanisms that regulate these interactions, which could lead to new therapeutic strategies for conditions like Amyotrophic Lateral Sclerosis. Patients may benefit from insights gained into improving recovery from nerve injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced peripheral nerve injuries or are affected by motoneuron diseases such as Amyotrophic Lateral Sclerosis.
Not a fit: Patients with non-neurological conditions or those who have not experienced nerve injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance nerve recovery and improve outcomes for patients with nerve injuries.
How similar studies have performed: Previous research has shown promising results in understanding microglial behavior in nerve injuries, indicating that this approach has potential for success.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POTTORF, TANA — EMORY UNIVERSITY
- Study coordinator: POTTORF, TANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease