Understanding how immune cell metabolism affects cancer treatment
Integrating systems immunology with immunometabolism and cancer immunity
['FUNDING_OTHER'] · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · NIH-10907564
This study is looking at how the energy and nutrients that immune cells use can help them fight cancer better, with the goal of finding new ways to improve cancer treatments for patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (nih funded) |
| Locations | 1 site (MEMPHIS, UNITED STATES) |
| Trial ID | NIH-10907564 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between the metabolic state of immune cells and their ability to fight cancer. By combining traditional research methods with advanced systems immunology, the team aims to uncover how immune cells can be better utilized in cancer therapies. The study focuses on how nutrients and immune signals influence the behavior of T cells, which are crucial for antitumor immunity. Insights gained from this research could lead to the development of more effective cancer treatments tailored to individual metabolic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with various types of cancer, particularly those who may benefit from enhanced immune responses.
Not a fit: Patients with non-cancerous conditions or those whose cancer is not responsive to immune-based therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatments that enhance the immune system's ability to combat tumors.
How similar studies have performed: Previous research in immunometabolism has shown promising results, indicating that understanding immune cell metabolism can significantly impact cancer treatment strategies.
Where this research is happening
MEMPHIS, UNITED STATES
- ST. JUDE CHILDREN'S RESEARCH HOSPITAL — MEMPHIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHI, HONGBO — ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Study coordinator: CHI, HONGBO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment, Cancers