Understanding how immune and microbial factors influence colorectal cancer
Integration of Immunology and Microbiology into Molecular Pathological Epidemiology of Colorectal Cancer
This study is looking at how your immune system, gut bacteria, and cancer cells work together in colorectal cancer, with the goal of understanding how things like diet and lifestyle can affect your risk, so that we can find better ways to prevent and treat the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10909330 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between immune cells, microbiota, and tumor cells in colorectal cancer and adenomas. By integrating immunology and microbiology into molecular pathological epidemiology, the project aims to uncover how various exposures and lifestyle factors contribute to the disease. It utilizes advanced statistical and computational methods to analyze tumor tissue datasets from diverse populations, assessing the role of diet and lifestyle in relation to cancer incidence. Patients may benefit from insights that could lead to improved prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of colorectal cancer or adenomas, as well as those interested in understanding the impact of lifestyle factors on their health.
Not a fit: Patients without any history of colorectal cancer or adenomas, or those not interested in the relationship between lifestyle and cancer, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new strategies for preventing and treating colorectal cancer.
How similar studies have performed: Other research has shown promising results in understanding the role of microbiota and immune factors in cancer, indicating that this integrative approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Ugai, Tomotaka — Brigham and Women's Hospital
- Study coordinator: Ugai, Tomotaka
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.