Understanding how IL-33 affects inflammation and fibrosis
Taming IL-33 to Control Inflammation and Fibrosis
This study is looking at how a protein called IL-33 affects inflammation and healing in the body, with the hope of finding new treatments for diseases that cause scarring and damage to different organs, which could help patients feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11061225 on NIH RePORTER |
What this research studies
This research investigates the role of interleukin-33 (IL-33) in inflammation and fibrosis, which are processes that can lead to various diseases affecting different organs. The study focuses on the full-length IL-33 precursor, exploring how it regulates inflammatory responses and wound healing. By examining the mechanisms of IL-33's action, the research aims to uncover potential therapeutic strategies for managing inflammatory fibrotic diseases. Patients may benefit from insights that could lead to new treatments targeting IL-33.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from inflammatory fibrotic diseases.
Not a fit: Patients with conditions unrelated to inflammation or fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively manage inflammation and fibrosis in various diseases.
How similar studies have performed: Previous research has shown promising results in targeting IL-33 for therapeutic purposes, indicating potential for success in this approach.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Luzina, Irina G. — University of Maryland Baltimore
- Study coordinator: Luzina, Irina G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.