Understanding how hydrogen sulfide affects susceptibility to influenza A virus infection
Deciphering mechanisms of hydrogen sulfide-induced susceptibility to influenza A virus infection
This study is looking at how being around hydrogen sulfide, a type of air pollution, might make it easier for people to get sick from the flu, and it’s designed for anyone interested in how air quality affects our health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11139838 on NIH RePORTER |
What this research studies
This research investigates the relationship between exposure to hydrogen sulfide (H2S) and the susceptibility to influenza A virus (IAV) infections. It aims to fill a critical knowledge gap regarding how environmental pollutants, specifically H2S, impact respiratory health and increase the severity of viral infections. The study will involve pre-exposing mice to H2S and then challenging them with IAV to observe the effects on their respiratory systems. The findings could provide insights into how air quality influences viral infections in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in areas with high levels of air pollution or those with occupational exposure to hydrogen sulfide.
Not a fit: Patients who do not have respiratory issues or are not exposed to environmental pollutants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of respiratory infections in populations exposed to air pollutants.
How similar studies have performed: While the interaction between hydrogen sulfide and influenza A virus is relatively novel, previous studies have shown that environmental factors significantly influence respiratory infections.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Rumbeiha, Wilson Kiiza — University of California at Davis
- Study coordinator: Rumbeiha, Wilson Kiiza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.