Understanding how human papillomavirus enters cells
Mechanisms of human papillomavirus entry
This study is looking at how the HPV virus gets into our cells and is trying to find new ways to treat and prevent HPV-related issues, like certain cancers and genital warts, by understanding the proteins and pathways involved in this process.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10890833 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which human papillomavirus (HPV) enters human cells, focusing on the role of specific proteins and pathways involved in this process. The team has discovered that HPV uses a unique transport pathway and identified a peptide that helps the virus penetrate cells. By studying these mechanisms, the research aims to uncover new targets for treatment and prevention of HPV-related diseases, including cancers and genital warts. This work builds on decades of prior research and aims to improve our understanding of HPV biology.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with HPV infections or those at risk of HPV-related diseases.
Not a fit: Patients who have already been vaccinated against HPV and have no current infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for HPV infections and associated cancers, improving patient outcomes.
How similar studies have performed: Previous research has shown success in understanding viral entry mechanisms, making this approach promising for future breakthroughs.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Dimaio, Daniel C. — Yale University
- Study coordinator: Dimaio, Daniel C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.