Understanding how human genetics changed over time through ancient and modern DNA
Characterizing modes of natural selection via diverse ancient and modern samples
['FUNDING_OTHER'] · BROWN UNIVERSITY · NIH-11099676
This project looks at ancient and modern human DNA to learn how populations mixed and adapted to new environments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BROWN UNIVERSITY (nih funded) |
| Locations | 1 site (PROVIDENCE, UNITED STATES) |
| Trial ID | NIH-11099676 on ClinicalTrials.gov |
What this research studies
Our genetic makeup is a blend of different ancestries, and this project explores how these mixtures have shaped human evolution. By examining DNA from ancient and modern people, we can learn how new genetic variations were introduced and how they helped populations adapt. This work helps us understand how natural selection has acted on our genes throughout history, especially after different groups of people mixed together. It provides insights into the genetic changes that allowed humans to thrive in various environments.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation or recruitment for a clinical intervention.
Not a fit: Patients seeking immediate clinical treatments or direct health interventions would not receive benefit from this basic science research.
Why it matters
Potential benefit: This research could help us better understand the genetic basis of human health and disease by revealing how our genes have evolved and adapted over time.
How similar studies have performed: Analysis of ancient genomes has already shown that population mixing is a major part of human history, and this project builds on those successful approaches by developing new statistical methods.
Where this research is happening
PROVIDENCE, UNITED STATES
- BROWN UNIVERSITY — PROVIDENCE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUERTA-SANCHEZ, EMILIA — BROWN UNIVERSITY
- Study coordinator: HUERTA-SANCHEZ, EMILIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.