Understanding how human genetic variations affect traits and disease risk
The origin, the function and the phenotypic impact of human alleles
This study is looking at how small differences in our genes can affect our health and the risk of diseases, helping us understand how these variations might influence you and your unique health journey.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10907418 on NIH RePORTER |
What this research studies
This research investigates the role of genetic variations, known as alleles, in influencing human traits and the risk of diseases. By analyzing how these variations affect molecular functions, the study aims to uncover the evolutionary processes that shape our genomes. Utilizing advanced computational methods and large sequencing datasets, the research will explore the origins of genetic variation and its implications for health. Patients may benefit from insights into how their unique genetic makeup can affect their health and disease susceptibility.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with known genetic variations or those interested in understanding their genetic predispositions to diseases.
Not a fit: Patients without significant genetic variation or those with conditions unrelated to genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic factors influencing health, potentially guiding personalized medicine approaches.
How similar studies have performed: Previous research has shown success in understanding genetic variations and their impact on health, making this approach both relevant and promising.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Sunyaev, Shamil — Harvard Medical School
- Study coordinator: Sunyaev, Shamil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.