Understanding how human cells grow and respond to cancer treatments
Computational Models of the Human Cell Cycle to Reveal Disease Mechanism and Inform Treatment
This study is looking at how cancer treatments affect the way human cells grow and respond, especially when they get damaged, to help find better ways to treat cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10670944 on NIH RePORTER |
What this research studies
This research focuses on creating computational models to predict how the human cell cycle reacts to various cancer treatments, such as radiation and targeted therapies. By using advanced imaging techniques, the team will analyze how cells behave during critical phases of their growth cycle, especially when they encounter DNA damage. The goal is to uncover the mechanisms that lead to abnormal cell growth and to improve treatment strategies for cancers. A collaborative team of experts from different fields will work together to integrate their findings into predictive models that can inform future clinical practices.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancers that involve abnormal cell proliferation and who are undergoing treatments like radiotherapy or targeted therapy.
Not a fit: Patients with non-cancerous conditions or those not receiving any form of cancer treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by providing insights into how cells respond to therapies.
How similar studies have performed: Previous research has shown promise in using computational models to understand cell behavior in response to treatments, indicating that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Purvis, Jeremy — Univ of North Carolina Chapel Hill
- Study coordinator: Purvis, Jeremy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.