Understanding how HPV infection affects oral cancer in HIV-positive individuals in Nigeria
Epigenetic study of oral HPV infection-associated oral cancer in people living with HIV in Nigeria
This study is looking at how HPV infections might affect the risk of oral cancers in people living with HIV in Nigeria, and it hopes to find ways to help prevent and catch these cancers early by understanding changes in gene activity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10913421 on NIH RePORTER |
What this research studies
This research investigates the link between Human papillomavirus (HPV) infections and oral cancers in people living with HIV in Nigeria. It aims to identify how epigenetic changes, which are modifications in gene expression, can indicate the risk of developing these cancers. By studying the prevalence of HPV and its interaction with HIV, the research seeks to develop targeted interventions for better prevention and early detection of oral and oropharyngeal cancers. Patients may be involved in providing samples and data to help understand these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for HPV infections and oral cancers.
Not a fit: Patients who do not have HIV or those without HPV infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and early detection methods for oral cancers in HIV-positive individuals.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between HPV and cancer in similar populations, indicating that this approach has potential for success.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Hou, Lifang — Northwestern University at Chicago
- Study coordinator: Hou, Lifang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.