Understanding how host traits influence the microbiome and its effects on health
Official title: Identifying the Drivers and Consequences ofHost-Microbiome Composition and Function
Funded at University of California, San Diego · NIH-10997009 · Data updated 2026-11-12
This study looks at how tiny organisms called unicellular algae and their helpful bacteria work together, focusing on how the algae's background and characteristics influence the types of bacteria they have, which can affect their health and well-being.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $41,957 |
| NIH project number | 1F31GM156042-01 |
| Project ID | NIH-10997009 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions influenced by microbiome health, such as gastrointestinal disorders or metabolic diseases.
✕Less likely to help
Patients with conditions unrelated to microbiome function or those who do not have a significant microbiome component in their health issues may not benefit from this research.
What this research studies
This research investigates the relationship between host organisms and their microbiomes, focusing on how the evolutionary history and traits of the host affect the composition and function of the microbiome. By using unicellular algae as a model system, the study aims to explore how closely related host species share similar microbiomes and how these microbiomes impact the health and physiology of the host. The research employs advanced sequencing techniques to analyze the microbial communities associated with different algal strains, providing insights into the complex interactions between hosts and their microbiomes.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of how microbiomes influence host health, potentially guiding new therapeutic strategies.
How similar studies have gone: Previous research has shown promising results in understanding microbiome dynamics in relation to host health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Broe, Taryn — University of California, San Diego
- Study coordinator: Broe, Taryn
Related research
Other NIH-funded projects on the same topics.
-
Improved MRI guidance for pediatric heart catheterization using autonomous multi-beat image synthesis
Aiming to make MRI-guided pediatric heart catheterizations safer and more reliable by using smart, multi-beat data fusion to produce clearer real-time MRI images.
-
Adapting a combination approach to reduce heavy drinking and boost HIV care and prevention among young men
A pilot project tests a proven program that helps young men cut down on heavy drinking and improves HIV treatment and prevention outcomes.
-
How specific anti-NMDAR1 antibodies in the blood may affect memory and brain protection
This research is exploring whether natural or abnormal anti-NMDAR1 antibodies in the blood influence memory, behavior, and brain protection in humans.
-
Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth
This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.
-
Pharmacometrics Core at UC San Diego
A pharmacometrics core is funded to support researchers in analyzing drug data to improve how medicines work for patients.
-
Milk Analytics Core for Precision Dairy Research
A core facility at UC San Diego will provide specialized milk analysis services to support research on dairy biology and human health.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.