Understanding how host traits influence the microbiome and its effects on health
Identifying the Drivers and Consequences ofHost-Microbiome Composition and Function
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10997009
This study looks at how tiny organisms called unicellular algae and their helpful bacteria work together, focusing on how the algae's background and characteristics influence the types of bacteria they have, which can affect their health and well-being.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10997009 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between host organisms and their microbiomes, focusing on how the evolutionary history and traits of the host affect the composition and function of the microbiome. By using unicellular algae as a model system, the study aims to explore how closely related host species share similar microbiomes and how these microbiomes impact the health and physiology of the host. The research employs advanced sequencing techniques to analyze the microbial communities associated with different algal strains, providing insights into the complex interactions between hosts and their microbiomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by microbiome health, such as gastrointestinal disorders or metabolic diseases.
Not a fit: Patients with conditions unrelated to microbiome function or those who do not have a significant microbiome component in their health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of how microbiomes influence host health, potentially guiding new therapeutic strategies.
How similar studies have performed: Previous research has shown promising results in understanding microbiome dynamics in relation to host health, suggesting that this approach could yield valuable insights.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BROE, TARYN — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: BROE, TARYN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.