Understanding how host genetics and environment shape microbiomes
Identifying the Rules Governing Host-Microbiome Composition and Function
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11083596
This study looks at how the genes of tiny plant-like organisms and their surroundings work together to affect the tiny microbes living with them, which could help us understand how these microbes impact the health of these organisms.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11083596 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between host genetics and environmental factors in shaping the composition and function of microbiomes associated with eukaryotic organisms. By using single-celled eukaryotic phytoplankton as a model system, the study aims to explore how these factors influence microbial community assembly and their potential impacts on host health. The research employs advanced bacterial gene expression techniques to analyze how microbiomes respond to genetic and environmental changes over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by microbiome health or those interested in understanding the role of their microbiome in overall health.
Not a fit: Patients with conditions unrelated to microbiome function or those not willing to engage in research related to microbiome studies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for maintaining and improving host health by optimizing microbiome composition.
How similar studies have performed: Previous research has shown promising results in understanding microbiome dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JACKREL, SARA LINDSAY — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: JACKREL, SARA LINDSAY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.