Understanding how hormones control reproduction and fertility
Official title: Reproductive physiology of gonadotropin synthesis
Funded at Brigham and Women's Hospital · NIH-11083141 · Data updated 2026-11-12
This study is looking into how certain hormones that help with fertility are controlled by signals from the brain and other hormones, with the goal of finding better ways to support reproductive health for people facing fertility challenges.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $561,295 |
| NIH project number | 5R37HD019938-33 |
| Project ID | NIH-11083141 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing fertility issues or hormonal imbalances related to reproductive health.
✕Less likely to help
Patients with reproductive health issues unrelated to gonadotropin regulation may not benefit from this research.
What this research studies
This research investigates the complex regulation of gonadotropins, which are hormones essential for fertility. It focuses on how the synthesis and secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are influenced by various signals from the brain and gonadal hormones. By using cellular, animal, and human models, the research aims to uncover the molecular mechanisms that govern these hormonal processes, ultimately seeking to improve reproductive health and address fertility issues.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for infertility and reproductive disorders.
How similar studies have gone: Previous research has shown success in understanding hormonal regulation of reproduction, making this approach both relevant and promising.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Kaiser, Ursula B. — Brigham and Women's Hospital
- Study coordinator: Kaiser, Ursula B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.